You replaced your original Enasaves at 44K miles...which were probably fairly worn at that point, right?
One thing to remember when tracking fuel mileage and you change tires is this: A new tire (of the same make/model) will always have higher rolling resistance than that same tire when it is worn out...because the new tire has more tread. Your worn out Low Rolling Resistance Enasaves were a very good tire for fuel mileage. They're lousy for everything else, but that's another story.
So you replaced a worn out Low Rolling Resistance tire with a brand new non-LRR tire. So you have 2 things going on:
1) You have a brand new tire with more tread...so it will naturally have more rolling resistance
2) You opted for tires that aren't Low Rolling Resistance tires...so you definitely lost some efficiency there
It's possible that those 2 things together may have cost you around 10% in a worst-case scenario. I would not expect your setup to cost you 10+ mpg. I wouldn't make any judgements until you have run a few tanks of gas on the new tires.
View my fuel log 2015 Mirage ES 1.2 manual: 52.1 mpg (US) ... 22.2 km/L ... 4.5 L/100 km ... 62.6 mpg (Imp)